This work provides guidance on how mathematical modelling should be employed to support country-level TB decision-making. It was developed by TB MAC and a wide collaboration of modelling stakeholders, and endorsed by the WHO Global Task Force on TB Impact Measurement in 2018. This guidance was then operationalised and piloted in the Benchmarking, Reporting and Review (BRR) framework. PDF versions of the guidance document and BRR framework are linked below along with a copy the brochure version which outlines some of the key components.